What Vellum does better than anything else
Vellum's output is the reason it costs $249 and the reason authors pay it. Hand it a finished manuscript and the book that comes back looks like a designer set it: chapter openers with ornaments, drop caps that sit correctly, running heads that behave all the way through a print PDF, and a preview that shows you the same page as a paperback, a Kindle and a phone at once. That reputation is earned, and a comparison that skipped over it would not be worth reading.
It is also close to effortless. Vellum ships 26 typefaces and a small set of book styles, and the small number is the point: there are few enough decisions that you cannot easily make the book ugly. For an author who wants a professional print interior without learning typesetting, that has been the shortest route available for years. Vellum exports EPUB, MOBI, PDF and DOCX, the $249 is one-time with future updates included, and the trial is unlimited; you can format the whole book and pay only when you want the files out.